pCBRG- STAT1 p84/p91 RE
CBV20042
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| Introduction | |
| Description: | pSTAT1 p84/p91 RE-Luc is designed for monitoring the induction of signal transducer and activator of transcription 1(p84/p91).The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. |
| Plasmid profile: |  |
| Unit Size: | 1-4μg |
| Pathway (Activitor): | STAT1 |
| Pathway profile: |  |
| Full Name: | Signal transducer and activator of transcription 1(p84/p91) |
| Cis response element: | stat1 p84/p91 RE |
| Shelf Life: | One year from date of receipt under proper storage conditions. |
| Storage: | -20°C |
| Mode of transportation: | Ice bag transport |
| Matters needing attention: | For your health, please wear lab clothes and disposable gloves. |
